| Title | EKSTRAK JAHE (Zingiber officinale Roscoe) PENGHAMBAT OKSIDASI LDL [Ginger (Zingiber officinale Roscoe) Extracts Inhibits LDL Oxidation] |
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| Author Order | of |
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| Abstract | Oxidative modification of LDL is believed to play an important role in atherogenesis.ÃÂÃÂ Dichloromethane extract of ginger rhizomes exhibited a strong antioxidative activity using linoleic acid as substrate.ÃÂÃÂ We investigated the in vitro effect of these extract enrichment on the prevention of oxidative LDL by CuSO4. Plasma was supplemented with 43, 430, or 4300 mg/ml dichloromethane extract in dimethylsulfoxide (DMSO) (10 ml DMSO per ml plasma), incubated, and the LDL was isolated.ÃÂÃÂ Lag phase and malonaldehide content was analized after the isolated LDL was oxidized using CuSO4.ÃÂÃÂ The result showed that dichloromethane extract of ginger rhizomes suplementation prolonged lag phase and reduced malonaldehide formation depended on its concentration.ÃÂÃÂ Concentration of 43 and 4300 mg/ml plasma of these extract reduced malonaldehide formation by 35,29 % and 69,72 % respectively, but not significant in prolonged lag phase.ÃÂÃÂ Concentration of these extract with largest prolonged lag phase (82,16 %) and reduced malonaldehide formation (74,95 %)ÃÂÃÂ was 430ÃÂÃÂ mg/ml plasma.ÃÂÃÂ This research has shown that ginger extract is capable of protecting LDL from oxidation.ÃÂÃÂ |
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| Publisher Name | Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI |
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| Publish Date | 2013-09-13 |
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| Publish Year | 2002 |
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| Doi | |
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| Citation | |
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| Source | Jurnal Teknologi dan Industri Pangan |
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| Source Issue | Vol. 13 No. 1 (2002): Jurnal Teknologi dan Industri Pangan |
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| Source Page | 70 |
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| Author | Dr Ir AISYAH TRI SEPTIANA, M.P |
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| File | 1315802.pdf |
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