The disruptive effect of mercury chloride (HgCl) on gene expression of gonadotrophin hormones and testosterone level in male silver sharkminnow (Osteochilus hasseltii C.V.) (Teleostei: Cyprinidae) (vol 84, pg 436, 2017)

Publons ID18581987
Wos IDWOS:000407954100045
Doi10.1080/24750263.2017.1352040
TitleThe disruptive effect of mercury chloride (HgCl) on gene expression of gonadotrophin hormones and testosterone level in male silver sharkminnow (<i>Osteochilus hasseltii</i> C.V.) (Teleostei: Cyprinidae) (vol 84, pg 436, 2017)
First AuthorSiregar, A. S.; Prayogo, N. A.;
Last Author
AuthorsSiregar, AS; Prayogo, NA;
Publish Date2017
Journal NameEUROPEAN ZOOLOGICAL JOURNAL
Citation5
AbstractEndocrine-disrupting compounds in water affect reproductive activities in fish. Mercury is a toxic and persistent pollutant, which bioaccumulates in the food chain. To investigate the effect of mercury chloride (HgCl) on fish reproduction, animals were kept in four aquaria containing increasing levels of HgCl (0 mg/L [control]; 0.025 mg/L [ low]; 0.05 mg/L [medium]; 0.1 mg/L [high]) for 60 days. The effects of HgCl on reproduction performance of male silver sharkminnow were evaluated by GtH-Ia, GtH-IIa and GtH-IIb gene expression, testosterone levels, and GSI levels. A significant decrease in Gonadothropin Hormone type I sub unit alpha (GtH-Ia), Gonadothropin Hormone type II sub unit alpha (GtH-IIa) and Gonadothropin Hormone type II sub unit beta (GtH-IIb) gene expression, testosterone levels, and Gonado Somatic Index (GSI) levels was detected in fish receiving the high mercury dose compared to controls after 2, 4, 6 and 8 weeks (P < 0.05). After 4, 6 and 8 weeks, all treatment groups had significantly lower GtH-Ia, GtH-IIa and GtH-IIb gene expression, testosterone levels and GSI levels compared to the control group (P < 0.05). These findings demonstrate a disruptive role of mercury on reproductive performance in male silver sharkminnow.
Publish TypeJournal
Publish Year2017
Page Begin436
Page End443
Issn2475-0263
Eissn
Urlhttps://www.webofscience.com/wos/woscc/full-record/WOS:000407954100045
AuthorDr NORMAN ARIE PRAYOGO, S.Pi, M.Si
File6547.pdf