Garuda Documents : Synthesis, Characterization, Antioxidant Activity, and Toxicity Properties of Tripolyphosphate Crosslinked Chitosan

TitleSynthesis, Characterization, Antioxidant Activity, and Toxicity Properties of Tripolyphosphate Crosslinked Chitosan
Author Order3 of 5
Accreditation
AbstractChitosan is biopolymer obtained from chitin deacetylation reaction. Chitin is a constituent of shrimps’ outer shell. Chitosan modification using crosslinker agent could increase the active groups and stabilize the physical character. One of non-toxic crosslink agents was tripolyphosphate. This study aimed at synthesizing tripolyphosphate crosslinked chitosan (TPP-Cs) to test the antioxidant and toxicity. Synthesizing tripolyphosphate chitosan was conducted using ionic gelation method. The antioxidant activity test was studied from DPPH radicals scavenging and the ability to inhibit linoleic acid oxidation. The toxicity test was using BSLT (Brine Shrimp Lethality Test) method and Artemia salina leach nauplii. The study showed that TPP-Cs could be synthesized from pink shrimp and showed antioxidant activity. The activity was due to amino and hydroxyl groups. The BSLT method showed that TPP-Cs had the potential to be applied for antibacterial, antivirus, or anticancer products.  
Publisher NameUniversitas Jenderal Soedirman
Publish Date2021-11-15
Publish Year2021
DoiDOI: 10.20884/1.jm.2021.16.3.815
Citation
SourceMolekul
Source IssueVol 16, No 3 (2021)
Source Page253-261
Urlhttps://ojs.jmolekul.com/ojs/index.php/jm/article/view/815/390
AuthorMARDIYAH KURNIASIH, S.Si, M.Sc.
File2512940.pdf