| Title | SINTESIS 6-NITRO VERATRALDEHID (3,4-DIMETOKSI-6-NITRO BENZALDEHID) DARI VANILIN DENGAN HNO3 DAN CAMPURAN HNO3-H2SO4 |
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| Author Order | 1 of 3 |
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| Accreditation | |
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| Abstract | The synthesis of 6-nitro veratraldehyde from vanillin was used HNO3ÃÂ and a mixture of HNO3ÃÂ and H2SO4. The reaction steps were (I) methylation of vanillin and (2) nitration of the methylation product. Methylation of vanillin was conducted using dimetnylsulfate and NaOH at 60ÃÂ 0C for 2 hours. Nitration of the methylation product was performed in two methods, which using HN03ÃÂ and using a mixture of HN03ÃÂ and H2SO4ÃÂ both at 5ÃÂ 0C for 2 hours. The products were analyzed by means of TLC, GC; IR,ÃÂ 1H-NMR and GC-MS spectrometers.The methylation of vanillin gave 87.7 % yield of veratraldehyde which was found as a white crystal (m.p 43ÃÂ oC). The nitration of veratraldehyde produced 6-nitro veratraldehyde observed as a yellow crystal having of m.p. 1300C. Nitration using neat HNO3ÃÂ gave a smaller yield (50.35%) of 6-nitro veratraldehyde than nitration with a mixture of HNO3ÃÂ and H2SO4ÃÂ (93.63 %). |
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| Publisher Name | Universitas Jenderal Soedirman |
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| Publish Date | 2009-11-01 |
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| Publish Year | 2009 |
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| Doi | DOI: 10.20884/1.jm.2009.4.2.64 |
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| Citation | 1 |
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| Source | Molekul |
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| Source Issue | Vol 4, No 2 (2009) |
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| Source Page | 62-72 |
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| Url | https://ojs.jmolekul.com/ojs/index.php/jm/article/view/64/58 |
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| Author | Dr. UNDRI RASTUTI, S.Si, M.Si |
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| File | 1251783.pdf |
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