Antibacterial Flavanones and Dihydrochalcones from Macaranga trichocarpa

Publons ID(not set)
Wos IDWOS:000348967800004
Doi10.5560/ZNC.2014-0066
TitleAntibacterial Flavanones and Dihydrochalcones from <i>Macaranga</i> <i>trichocarpa</i>
First Author
Last Author
AuthorsFareza, MS; Syah, YM; Mujahidin, D; Juliawaty, LD; Kurniasih, I;
Publish DateSEP-OCT 2014
Journal NameZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
Citation17
AbstractPreviously we had isolated two prenylated flavanones and two prenylated dihydrochalcones, macatrichocarpins A-D (1-4), from the acetone extract of the leaves of Macaranga trichocarpa. Re-examination of the fractions containing minor components resulted in the isolation of four more flavonoid derivatives, including two new prenylated dihydrochalcones, oxymacatrichocarpin C (5) and isomacatrichocarpin C (6). The structures of these compounds were determined by the analysis of UV, NMR, and mass spectral data. The eight isolated flavonoids were tested on eight pathogenic bacteria and found to be mostly moderate antibacterial agents, with the lowest MIC value of 26.5 mu M achieved by the flavanone macatrichocarpin A (1) against Bacillus subtilis.
Publish TypeJournal
Publish Year2014
Page Begin375
Page End380
Issn0939-5075
Eissn
Urlhttps://www.webofscience.com/wos/woscc/full-record/WOS:000348967800004
AuthorDr MUHAMAD SALMAN FAREZA, M.Si
File80835.pdf