| Publons ID | 43718744 |
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| Wos ID | WOS:000486458400025 |
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| Doi | 10.1007/978-1-4939-9438-0_24 |
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| Title | Enantioseparation of Selected Imidazole Drugs Using Dual Cyclodextrin-Modified Micellar Electrokinetic Chromatography |
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| First Author | |
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| Last Author | |
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| Authors | Ibrahim, WAW; Abd Wahib, SM; Hermawan, D; Sanagi, MM; |
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| Publish Date | 2019 |
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| Journal Name | CHIRAL SEPARATIONS: METHODS AND PROTOCOLS, 3RD EDITION |
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| Citation | 1 |
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| Abstract | Particular attention has been paid to capillary electrophoresis as versatile and environmentally friendly approach for enantioseparations of a wide spectrum of compounds. Cyclodextrin-modified micellar electrokinetic chromatography (CD-MEKC) is a method of choice to provide effective separation toward hydrophobic and uncharged stereoisomers. The chiral discrimination of the solutes relies upon the partitioning between a given CD in the aqueous phase and micelles formed from a surfactant. Synergistic combinations of chiral selectors, surfactant, and modifier contribute to successful enantioseparations of the enantiomers. In this chapter, an application of CD-MEKC for the enantioseparation of selected imidazole drugs employing a dual CDs system is described. |
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| Publish Type | Book in series |
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| Publish Year | 2019 |
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| Page Begin | 407 |
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| Page End | 416 |
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| Issn | 1064-3745 |
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| Eissn | 1940-6029 |
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| Url | https://www.webofscience.com/wos/woscc/full-record/WOS:000486458400025 |
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| Author | DADAN HERMAWAN |
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| File | 55707.pdf |
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