| Publons ID | 41312942 |
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| Wos ID | WOS:000399169500011 |
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| Doi | 10.1088/1757-899X/172/1/012011 |
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| Title | Development of high performance liquid chromatography method for miconazole analysis in powder sample |
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| First Author | |
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| Last Author | |
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| Authors | Hermawan, D; Suwandri; Sulaeman, U; Istiqomah, A; Aboul-Enein, HY; |
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| Publish Date | 2017 |
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| Journal Name | MATERIAL CHEMISTRY DEVELOPMENT FOR FUTURE MEDICINE, INDUSTRY, ENVIRONMENTAL AND BIOMATERIAL APPLICATION |
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| Citation | 3 |
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| Abstract | A simple high performance liquid chromatography (HPLC) method has been developed in this study for the analysis of miconazole, an antifungal drug, in powder sample. The optimized HPLC system using C-8 column was achieved using mobile phase composition containing methanol: water (85: 15, v/v), a flow rate of 0.8 mL/min, and UV detection at 220 nm. The calibration graph was linear in the range from 10 to 50 mg/L with r(2) of 0.9983. The limit of detection (LOD) and limit of quantitation (LOQ) obtained were 2.24 mg/L and 7.47 mg/L, respectively. The present HPLC method is applicable for the determination of miconazole in the powder sample with a recovery of 101.28 % (RSD = 0.96%, n = 3). The developed HPLC method provides short analysis time, high reproducibility and high sensitivity. |
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| Publish Type | Book in series |
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| Publish Year | 2017 |
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| Page Begin | (not set) |
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| Page End | (not set) |
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| Issn | 1757-8981 |
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| Eissn | |
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| Url | https://www.webofscience.com/wos/woscc/full-record/WOS:000399169500011 |
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| Author | UYI SULAEMAN, S.Si, M.Si, PhD |
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| File | 55706.pdf |
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